Aspirin should be offered to Lynch syndrome patients

Patients with the inherited genetic condition have an increased lifetime risk estimated to be four out of five people of developing colorectal cancer, and until now regular screening with colonoscopy and polypectomy to identify pre-cancerous cells has been the main strategy to detect early colorectal cancer in those susceptible. NICE previously published diagnostics guidance in 2017 recommending that everyone who is diagnosed with colorectal cancer should be tested for LS, and if the test shows they do have LS, they can be monitored for other cancers and their close relatives can also be offered testing for LS. Updated guidance recommends aspirin is an option to reduce the risk of colorectal cancer among this group.

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