Date: 15-Oct-2020

Glenmark Pharma Launches Generic Nintedanib To Treat Pulmonary Fibrosis In India

Glenmark Pharma announced the launch of generic version of Nintedanib (Nindanib), used for the treatment of pulmonary fibrosis in India.

Glenmark being a leader in the area of respiratory has been amongst the first to launch the branded generic version at an affordable cost for the treatment of pulmonary fibrosis in India.

This will provide patients a far more cost effective treatment option, and enable doctors to treat a wider patient population in the country.

Glenmark’s Nindanib priced at Rs. 4,500 (100 mg) and Rs. 5,400 (150 mg) per month is just available at 5% of the cost as compared to the innovator brand in India.

Nintedanib is approved by the Indian drug regulator for the treatment of Idiopathic (unknown cause) pulmonary fibrosis (IPF).

"Since IPF is a progressive disease that gets worse over time, starting treatment early and continuing treatment are important to slow disease progression.

"A lower monthly treatment cost therefore becomes crucial to ensure patients adhere to prescribed treatment in the long term. So far, Nintedanib has been studied extensively in various controlled clinical trials that have established its efficacy and safety," the company added.

Glenmark said two clinical trials are being rolled out to study the efficacy and safety of Nintedanib as a treatment of SARS-COV2 induced pulmonary fibrosis in moderate to severe COVID-19 patients.

So far Nintedanib has been studied extensively in various controlled clinical trials that have established its efficacy and safety. In a recently published INBUILDtm trial, Nintedanib showed significantly lower annual rate of decline in FVC (forced vital capacity) – a measure of lung health – with various progressive fibrosing interstitial lung diseases.

"With limited treatment options available, interstitial lung diseases pose a significant treatment challenge in India. The high price of newer treatments and the pill burden of existing options only add to poor patient adherence. By introducing Nindanib, we hope to substantially reduce both the pill and cost burden for patients in India,” said Alok Malik, group vice president & business head, India Formulations. He added, “Glenmark continues to invent and innovate healthcare solutions that meet specific and often hard-to-address needs of patients in India and the world.”